Enzyme engineering: reaching the maximal catalytic efficiency peak
نویسندگان
چکیده
منابع مشابه
Dynamical contribution into enzyme catalytic efficiency
A realistic physical model for the so called rate promoting vibration (RPV) at enzyme action is constructed. The origin of the RPV is assumed to be an oscillating electric field produced by long-lived localized vibrational modes in protein dynamics, namely, by the so called discrete breather (DB) in secondary structure. The strength of interaction of the RPV with the reaction coordinate is eval...
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A realistic physical model for the so called rate promoting vibration (RPV) at enzyme action is constructed. The origin of the RPV is assumed to be an oscillating electric field produced by long-lived localized vibrational modes in protein dynamics, namely, by the so called discrete breather (DB) in secondary structure. The strength of interaction of the RPV with the reaction coordinate is eval...
متن کاملJa n 20 06 Dynamical contribution into enzyme catalytic efficiency
A realistic physical model for the so called rate promoting vibration (RPV) at enzyme action is constructed. The origin of the RPV is assumed to be an oscillating electric field produced by long-lived localized vibrational modes in protein dynamics, namely, by the so called discrete breather (DB) in secondary structure. The strength of interaction of the RPV with the reaction coordinate is eval...
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BACKGROUND Exercise capacity assessed by cardiopulmonary exercise testing is usually measured by peak oxygen consumption (VO2). However, not uncommonly, patients achieve a relatively higher work load (peak work) compared to their peak VO2. In these situations it is difficult to know which parameter to use in assessing exercise capacity. The purpose of this study was to determine whether there a...
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ژورنال
عنوان ژورنال: Current Opinion in Structural Biology
سال: 2017
ISSN: 0959-440X
DOI: 10.1016/j.sbi.2017.09.002